Tributyrin (TB)ndiMonolaurin (GML)Monga zowonjezera zakudya, zimakhala ndi zotsatira zambiri pa ulimi wa nkhuku zoyamwitsa, zomwe zimapangitsa kuti mazira azigwira bwino ntchito, ubwino wa mazira, thanzi la m'mimba, komanso kagayidwe ka mafuta m'thupi. Nazi ntchito ndi njira zawo zazikulu:

1. Kukweza momwe mazira amapangira
Glycerol Monolaurate(GML)

Kuwonjezera 0.15-0.45g/kg GML pa zakudya za nkhuku zoyamwitsa kungathandize kwambiri kupanga mazira, kuchepetsa kuchuluka kwa chakudya chosinthidwa, komanso kuwonjezera kulemera kwa mazira.
Kafukufuku akusonyeza kuti 300-450mg/kg GML imatha kukweza kuchuluka kwa mazira a nkhuku zoyamwitsa ndikuchepetsa kuchuluka kwa mazira olakwika.

Tributyrin (TB) 

Mu kuyesa nkhuku za broiler, 500mg/kg TB imatha kuchedwetsa kuchepa kwa kupanga mazira kumapeto kwa nthawi yoika mazira, kulimbitsa mphamvu ya chipolopolo cha dzira, komanso kuchepetsa kuchuluka kwa kuswana.
Kuphatikiza ndiGML(monga njira yovomerezeka) ingawonjezere nthawi yopangira dzira lalikulu ndikuwonjezera phindu lazachuma.

2. Konzani ubwino wa dzira

Ntchito ya GML
Wonjezerani kutalika kwa mapuloteni, ma Haff units (HU), ndikuwonjezera mtundu wa yolk.
Sinthani kapangidwe ka mafuta acid mu yolk ya dzira, onjezerani polyunsaturated fatty acids (PUFA) ndi monounsaturated fatty acids (MUFA), ndikuchepetsa kuchuluka kwa mafuta acids (SFA).

Pa mlingo wa 300mg/kg, GML inawonjezera kwambiri kuuma kwa chipolopolo cha dzira ndi kuchuluka kwa mapuloteni oyera a dzira.

Ntchito yaTB

Wonjezerani mphamvu ya zipolopolo za mazira ndikuchepetsa kuchuluka kwa kusweka kwa zipolopolo (monga kuchepetsa 58.62-75.86% mu kuyesa).

Limbikitsani kufalikira kwa majini okhudzana ndi kuikidwa kwa calcium m'chiberekero (monga CAPB-D28K, OC17) ndikuwonjezera kuchuluka kwa calcium m'chigoba cha dzira.

3. Kulamulira kagayidwe ka mafuta m'thupi ndi ntchito yoteteza thupi ku ma antioxidants
Ntchito ya GML
Kuchepetsa triglycerides m'magazi (TG), cholesterol yonse (TC), ndi cholesterol yotsika kwambiri (LDL-C), ndikuchepetsa mafuta m'mimba.
Kuwongolera ntchito ya serum superoxide dismutase (SOD) ndi glutathione peroxidase (GSH Px), kuchepetsa kuchuluka kwa malondialdehyde (MDA), ndikuwonjezera mphamvu ya antioxidant.
Ntchito yaTB
Chepetsani kuchuluka kwa triglycerides m'chiwindi (10.2-34.23%) ndikuwonjezera majini okhudzana ndi okosijeni wa mafuta (monga CPT1).
Kuchepetsa kuchuluka kwa alkaline phosphatase (AKP) ndi MDA m'magazi, ndikuwonjezera mphamvu yonse ya antioxidant (T-AOC).

4. Kulimbitsa thanzi la m'mimba
Ntchito ya GML
Wonjezerani kutalika kwa chipolopolo ndi chiŵerengero cha chipolopolo ku chipolopolo (V/C) cha jejunum kuti muwongolere mawonekedwe a m'mimba.
Chepetsani zinthu zomwe zimayambitsa kutupa (monga IL-1 β, TNF-α), onjezerani zinthu zomwe zimayambitsa kutupa (monga IL-4, IL-10), ndikuwonjezera ntchito yotchinga matumbo.
Konzani bwino kapangidwe ka cecal microbiota, chepetsani kuchuluka kwa ma Proteobacteria, ndikulimbikitsa kukula kwa mabakiteriya opindulitsa monga Spirogyraceae.
Ntchito ya TB
Sinthani pH ya m'matumbo, limbikitsa kuchulukana kwa mabakiteriya opindulitsa (monga lactobacilli), ndikuletsa mabakiteriya owopsa.
Kuwonjezeka kwa mapuloteni ogwirizana (monga Occludin, CLDN4) kumawonjezera kulimba kwa zotchinga m'mimba.

5. Mphamvu yolamulira chitetezo cha mthupi
Ntchito ya GML
Kuwongolera index ya spleen ndi index ya thymus, kumawonjezera ntchito ya chitetezo chamthupi.
Chepetsani zizindikiro zotupa m'magazi monga aspartate aminotransferase (AST) ndi alanine aminotransferase (ALT).
Ntchito ya TB
Chepetsani kutupa m'matumbo mwa kulamulira njira ya Toll-like receptor (TLR2/4).

6. Kugwiritsa ntchito pamodzi
Kafukufuku wa patent wasonyeza kuti kuphatikiza kwa GML ndi TB (monga 20-40 TB+15-30 GML) kungathandize kuti nkhuku zoyamwitsa zibereke mazira (92.56% vs. 89.5%) zibereke mazira (92.56% vs. 89.5%), kuchepetsa kutupa kwa ma tubes, ndikuwonjezera nthawi yopangira mazira ambiri.

Chidule:

Glycerol Monolaurate (GML)ndiTributyrin (TB)zimathandizanso pa ulimi wa nkhuku:

GMLimayang'ana kwambiri pakukonza ubwino wa dzira, kuwongolera kagayidwe ka mafuta m'thupi, ndi ntchito yoteteza ku ma antioxidants;
TBimayang'ana kwambiri pakukonza thanzi la m'mimba ndi kagayidwe ka calcium;
Kuphatikizaku kungathezimathandiza kuti mazira azigwira ntchito mogwirizana, komanso kuti azigwira bwino ntchito yobereka komanso kuti azibereka bwino.